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The History of Blood Cell Labeling 2002 - 2013

 


Cerfiticate Programme on Radiolabeling of Blood Elements

IZMIR, Turkey, October 5 - 7, 2012
Venue: Institute of Nuclear Sciences,
Ege University, Izmir, Turkey

ISORBE Education Committee: Victoria Soroa, Firat Gungor, Josep Martin-Comin, Kutlan Ozker, Christopher Palestro, Alberto Signore, Helmut Sinzinger

Course Director: Prof. Perihan Unak PhD, Co-Director: Assoc. Prof. Turkan Ertay, PhD  

Local Organization Committee: Fazilet Z. Biber Muftuler, Serap Teksoz, Fatma Y. Lambrecht 
 

Entry Requirements: B.Sc. degree majored in one of the Natural Sciences. Priority will be given to the candidates who have experience in the field.

Program Duration: 3 day didactic lectures and practicals, 12 week internship term (on the job training in an accepted facility under the supervision of an accepted tutor). The internship term can be spent in candidates' own country or a regional facility. The ISORBE education committee will work with the participants to find a suitable facility for their practical terms.

Registration Fee: Euro 50.00

Certificate: The candidate who has successfully completed the formal training and internship terms will be awarded by ISORBE “Certificate on Radiolabeling of Blood Cells”.  Please note that the ISORBE Certificate on Radiolabeling of Blood Cells does not substitute for national and/or regional legal or regulatory provisions.

List of participants: Ayse Esra Arslan, Aslan Aygün, Burcu DirliSerim, Derya Sahin, Ebru Salmanoglu, Esra Alkan Ciftci, Habibe Güldem Mercanoglu, Harun Kazanci, Inanc Karapolat, Mine Sencan, Mohamed Hamrouni S. Abushhiwa, Neslihan Incili Artut, Nurhan Ergül, Özden Ülker, Özge Er, Payam Mohorammi, Rumeysa Tutar, Sabire Yilmaz Aksoy, Volkan Tekin, Hend Alotaibi, Maryam Abujarva, Emrah Birol, Baris Barlas.

 


                   

 





Participants of the Certificate Programme on Radiolabeling of Blood Elements




Kutlan ÖZKER giving practial advice







In the ALASBIMN MEETING 2011 many ISORBE members were invited as official  speakers  for the Infection/Inflammation Meeting (Dr Christopher PALESTRO, Dr Jose MARTIN-COMIN, Dr Helmut SINZINGER(could not go) & Dra Victoria E. SOROA, among other invited speakers).

Below is the full agenda of the course:
 
3. CURSO DE INFECÇÃO/INFLAMAÇÃO
Comitê de Infecção/Inflamação: Dr. Carlos Anselmi (Brasil) and Dra Victoria Soroa (Argentina)
08:30

Infection/Inflammation Status in Argentina: Victoria Soroa (Argentina)
 09:00
 
INTERVAL
 
PET for Infection: FDG and Other Tracers: Christopher Palestro (USA)
10:30 
 
Radiological Diagnosis of Acute and Chronic Osteomyelitis: Carlos Anselmi (Brazil)
11:00 
 
Scintigraphic Diagnosis of Acute and Chronic Osteomyelitis: Javier Vilar (Uruguay)
11:30
 
LUNCH
 
New Tracers for Abdominal Infection and Inflammation: Dr Josep Martin Comin was suggested by Dra Soroa
14:00
 
FDG-PET in the Detection of Vulnerable Atherosclerotic Plaque: Dr Luís Illanes
14:30
 
Ga-68 PET for Infection: Vijay Kumar (Australia)
15:00

Nuclear Medicine in the Evaluation of Painful Orthopedic Prosthesis: Christopher Palestro (USA)
15:30


15th ISORBE Congress       
 

The 15th ISORBE Congress was held in NIJMEGEN, The Netherlands from March 31 to April 2, 2011
Congress President: Wim OYEN, Radbound University Nijmegen, The Netherlands 
Organisation: Wim OYEN and Otto  BOERMAN
Lectures by: H. Balink, R. Bennink, M. Bernardo Filho, C. Bleeker-Rovers, O. Boerman, J. Buscombe, M. Chianelli, M. Gotthardt, Ruth Keijers, J. Martin-Comin, M. Netea, W. Oyen, K. Ozker, C. Palestro, N. Prandini, A. Signore, H. Sinzinger, S. Srivastava, Victoria Soroa, M. Thakur, F. Vos, Jolanda de Vries
 
Participants: Maryam Abu Jarwa, H. Alotaibi, Anne Arens, Marie Claire Attard, J. Baas, H. Balink, Christel Baudin, R. Bennink, M. Mernardo-Filho, Chantal Bleeker-Rovers, O. Boerman, Desiree Bos, W. Bouwman, W. van den Broek, W. van der Bruggen, J. Buscombe, J. Butter, M. Chianelli, L. Claessens-Joost, Sandra Dahm, D. van Dijk, Ingrid Dijkgraaf, J. Disselhorst, Marielle Eikhof, G. Franssen, F. Gemmel, E. Geven, A. Glaudemans, G. Gonzales, M. Gotthardt, P. de Haas, F. Hajos, P. Hebels, Sandra Heskamp, Hana Hourani, A.W.L.C. Huiskes, M. Janssen, Ilse Janssen, Ruth Keijsers, Hilda Kleibergen, J. de Klerk, P. Kok, V. Kumar, M. Larikka, P. Laverman, Susanne Luttje, Julie Martin, J. Martin-Comin, J. Molkenboer, M. Netea, A. Oostdijk, W. Oyen, K. Özker, C. Palestro, H. van der Pol, R. Point. J.W. Postema, N. Prandini, Ruud Ramakers, M. van Riel, A. Signore, H. Sinzinger, F. Sivro, Grazyna Sobal, Victoria Soroa, S. Srivastava, Georga Stamatia, C. Stevens, M. Thakur, Eva Trifina, D. Valk, M. van de Ven, Annibale Versari, F. Vos, Jolanda de Vries, Edith Wesselink, T. Wetzels, A. Xing, M. Zuijdwijk

Congress website: http://www.umcn.nl/isorbe

                     

 

 

The meeting was open to all doctors and scientists interested in (molecular) imaging of inflammation and infection. The meeting provided lectures on clinical background, radiopharmaceuticals, basic and clinical imaging studies and imaging possibilities. Additionally, there were sessions scheduled for the presentation of selected abstracts.
 

 

Congress President Wim OYEN welcomes the participants

  
MINUTES of the ISORBE General Members Assembly, 31st March 2011:

The meeting was scheduled at 04:30 p.m. As less than 33% of the members were present (§ 15 by-laws), the meeting was postponed for 30 minutes. At 05:00 p.m. the president VictoriaSoroa welcomes the members who already paid their fee and is going through the agenda. H. Sinzinger has been asked to draft the minutes. (Delegation: C. Palestro to H. Sinzinger)

 

1.  Victoria Soroa presented her presidential report, thanking all the ISORBE-members and in particular presidium for their help and support over the last 4 years.

 

2.  The Treasurer presented the financial report, attendants got a handout-copy. For the auditors, J. Martin-Comin provided a statement that he controlled the finances and found everythin in order.

 

3.  The § 10 on the number of members of the Presidium was changed to “8 up to 10 members” and approved (concordantly).

 

 

4.  Throughout the by-laws “Newsletter” should be exchanged to “News” (approved concordantly).

5.  The offer of Mike Sathekge to organize the forhcoming ISORBE Conferene in 2013 in South Africa was accepted, details are to be worked out by the new presidium.

 
 

6.  For the 4 vacant positions for Presidium 4 candidates (were) applied in time and fulfilling the criteria to the by-laws. The candidates are F. Güngör, W. Oyen, Victoria Soroa, K. Özker. Their candidature was concordantly accepted. For the Board of Directors V. Kumar and A. Signore were approved. The other proposed candidates not being members or not having paid ISORBE fee yet were not considered for that position at this time.

 

7.  Grazyna Sobal was accepted as News Editor, her responsibility being homepage and news.

 

8. The ISORBE members were expressing their gratitude to the host, Wim Oyen, for organizing an excellent meeting and for his activities for ISORBE.

 

End of the meeting: 06:05 p.m.

For the protocol: Victoria Soroa and H. Sinzinger
 

MINUTES of the ISORBE Presidium Meeting, 1st April 2011:
Present: Victoria Soroa, H. Sinzinger, J. Martin-Comin, M. Chianelli, W. Oyen, F. Güngör, K. Özker
The meeting was called to order by Dr. Soroa at 08:30 a.m. (Delegation: C. Palestro to H. Sinzinger)
 
Kutlan Özker was unanimously elected as ISORBE President.
Fırat Güngör was elected as the secretary of ISORBE.
Helmut Sinzinger was unanimously elected for a further term as the treasurer of ISORBE. Josep Martin-Comin and Mario Bernardo-Filho were unanimously elected as auditors.

The meeting was closed at about 09:00 a.m.
For the protocol: Firat Güngör



2nd Blood Cell Radiolabeling Certificate Course
ANTALYA, Turkey, March 27 - 29, 2011
Venue: Akdeniz University Guest House, Antalya, Turkey
Organisation: Firat GÜNGÖR, Akadeniz University Antalya, Turkey,

ISORBE Education Committee: Victoria Soroa, Josep Martin-Comin, Kutlan Özker, Christopher Palestro, Alberto Signore, Helmut Sinzinger
Entry requirements: B.Sc. degree majored in Nuclear Medicine Technology or in one of the Natural Sciences. Priority will be given to the candidates who have experience in the field.

 

Open or closed systems for the labeling of cells?

Aseptic procedures should be used during blood cell isolation and labeling. To achieve this aim several closed systems have been developed in the past years.

Laboratory requirements: vary from country to country but they follow similar regulations as for the preparation of radioactive kits for clinical nuclear medicine. Unless a closed system is used, the laboratory should have defined specifications for cleanness, laminar airflow, particulate and microbiological contamination.
Victoria Soroa, President


Course schedule for ISORBE certificate program on radiolabeling of blood cells:

 

DAY 1

DAY 2

DAY 3

Lect. 1- General introduction to course

9:00-10:00

(V. Soroa)

 

Lect. 2- Radiolabeling of red blood cells (in vivo, in vi-vitro, in vitro)   

10:00-11:00

(V. Soroa, K. Ozker)

 

Lect. 3- Radiolabeling of white blood cells with In-oxine and Tc-99m-HMPAO

11:30-12:30

(F. Gungor, K. Ozker)

Lect. 4- Operation of a cell labeling facility, basic aspects, design of facilities, environmental controls, records.

9:00-10:00

(F. Gungor, K. Ozker)

 

Lect. 5- Infection and inflammation imaging (soft tissue)

10:00-11:00

(J. Martin-Comin)

 

Lect. 6- Infection and inflammation imaging (bone)

11:30-12:30

(J. Martin-Comin)

 

Lect. 7- Radiolabeling of platelets with In-111 oxine and Tc-99m- HMPAO 

9:00-10:00

(H. Sinzinger)

 

Lect. 8- Platelet dynamics, physiological aspects and pharmacokinetics. Clinical applications of radiolabeled platelets.

10:30-12:00

(H. Sinzinger)

Practical 1:

Radiolabeling of white blood cells with In-111 oxine

14:00-16:00

(F. Gungor, K. Ozker)

Practical 2:

Radiolabeling of red blood cells with Tc-99m

16:30-17:30

(V. Soroa, K. Ozker)

Practical 3:

Radiolabeling of white blood cells with Tc-99m-HMPAO

14:00-16:00

(F. Gungor, K.Ozker)

 

 

 

Practical 4:

Radiolabeling of platelets with In-111 oxine and Tc-99m-HMPAO

14:00-17:30

(H. Sinzinger)

 

 

2nd Blood Cell Radiolabeling Certificate Course - Report

Akdeniz University, Turkey 27- 29 March 2011 

  1. There was an ISORBE consensus statement about the minimum requirements necessary for a cell labeling facility and minimum requirements for the training of staff. [Eur J Nucl Med Mol Imaging (2009) 36:1351-1352]. Training on the radiolabeling of blood elements is directly related to the safety of patients as well as workers. The first training program was organized in Dubai by the Dubai Health Authority and ISORBE in 2009.
  2. This second course was organized by ISORBE and Akdeniz University Department of Nuclear Medicine, Antalya, Turkey.  
  3. ISORBE Education Committee was: Victoria Soroa, Helmut Sinzinger, Firat Güngör, Christopher Palestro, Josep Martin-Comin, Kutlan Özker.  The Director of the 2nd Blood Cell Radiolabeling Certificate Course was Professor Firat Güngör. 
  4. The course was attended by 21 fully registered participants from Turkey, 1 from Kuwait and 1 from Iran. There was a registration fee of 50 Euros which covered the attendance in didactic and practical sessions, coffee breaks, lunch and dinner for 3 days during the course.   
  5. The course contained theoretical and practical sessions (a copy of the Scientific Program is attached). 
  6. In the practical sessions erythrocytes, leukocytes and platelets radiolabeling were demonstrated using updated standard ISORBE procedures. Leukocytes radiolabeling resulted in 78% and 94% efficiency using Tc-99m HMPAO and In-111 oxine respectively, while platelets radiolabeling using In-111 oxine gave 97%.  HMPAO kits and In-111 oxine were gifts to the ISORBE Certificate Course respectively from Medi-Radiopharma, Hungary and Covidien.  
  7. It was also required that further practical work to be carried out at the workplace of individual participant as implementation of what have been learned during the course. The period of this on the job training was estimated to be about 3 months under the supervision of a tutor accepted by ISORBE. A total of 15 leukocyte labeling, 15 erythrocyte labeling and 5 platelet labeling (optional) were required from each participant in order to award the ISORBE Certificate for Radiolabeling of Blood Cells. 
  8. The course has been evaluated by the participants during a round table discussion on the last day of the program. The participants expressed that the course was very helpful to them and the aim of the course was completely fulfilled by 3 working days of didactic class room hours in the mornings and practical in the afternoons.  The participants in general found a good communication link with the faculty and required to be involved in the practical sessions rather than only observing the procedures. 
  9. More interactive programs will be implemented in the coming years. Updating and planning these training programs globally at different regions in the radiolabeling of blood cells will result in improved patient care and safety.

K. Özker


SPONSORS: MNT, Turkey; RADMED, Turkey; NEPHA, Turkey, Eczacibasi-Montrol, Turkey; Medicheck, Turkey; Medi-Radiopharma, Hungary; Covidien, The Netherlands.
HMPAO kits are gifts from Medi-Radiopharma, In-111 is a gift from Covidien.

ISORBE Certificate Leena DEEB:
/content_upload/files/ISORBE%20Certificate%20Leena%20Deeb.doc


/content_upload/files/RADIOLABELING%20OF%20BLOOD%20CELLS%20%20Leena.doc

/content_upload/files/Leena%20Deeb%20(c1).doc

ISORBE Certificate Funda AYDIN:
/content_upload/files/ISORBE%20certificate%20Funda%20Aydin%20(c1).doc

/content_upload/files/WBC%20labeling%20efficiencies.doc


     
Participants at lecture room                                                                                      Kutlan ÖZKER giving his practical advice

       
(from the left) Helmut SINZINGER, Victoria SOROA and                                Discussion with participants while cells were radiolabeled
 Kutlan ÖZKER at the Akdeniz University in Antalya during a break


         
   During a break at the roof terrace                                                                       Participants of the 2nd ISORBE Blood Cell Radiolabeling
                                                                                                                                                           Certificate Course



    
(from the left) Victoria SOROA, Firat GÜNGÖR and Kutlan ÖZKER                           Evening in the old town Antalya
                    during a walk through the bazaar in Antalya

 
 

 

ISORBE Meeting Dinner at the EANM Conference, Vienna, Austria, Oct. 12th, 2010 
 

 

(from the left) Helmut SINZINGER, Kutlan ÖZKER, Jose MARTIN-COMIN,
Victoria SOROA, Suresh SRIVASTAVA  at the "Pfarrwirt" in Vienna



ISORBE Plenary and CME Session at the WFNMB Congress
 CAPE TOWN, South Africa, September 21 - 22, 2010
"Inflammation & Infection"
Chair: Victoria SOROA, Mathew THAKUR
Lectures by: C. Palestro, V. Kumar, S. Srivastava, E. Lazzeri, A. Signore, M. Thakur, M. Sathekge, J. Buscombe, J. Martin-Comin, H. Sinzinger

 



 


The 10th World Federation of Nuclear Medicine & Biology Congress took place in Cape Town, South Africa from September 18 – 23, 2010. The WFNMB congress 2010 provided attendees with up-to-date information in Nuclear Medicine, as well as an opportunity to interact with Nuclear Medicine experts from around the world. ISORBE was given the responsibility for organizing plenary and continuing education sessions on infection and inflammation that were offered during the Congress. World renowned experts lectured on musculoskeletal and soft tissue infections, AIDS, the role of SPECT/CT and PET/CT in infection and inflammation, and new agents under investigation.

CME Session I
Tuesday September 21, 2010 (16:15-17:45)
Inflammation & Infection : AIDS, Mycobacterial, Vascular and FUO
Moderator:Christopher J. Palestro Co-Moderator: Alberto Signore
1. Nuclear Medicine & AIDS (30 min) (M. Sathekge)
2. Granulomatous Diseases (Mycobacterial infections & Sarcoid) (20 min) (J. Buscombe)
3. Prosthetic Vascular Graft Infection (20 min) (J. Martin-Comin)
4. Fever of Unknown Origin (20 min) (J. Buscombe)

CME Session II
Wednesday September 22, 2010 (8:00- 9:30)
Inflammation & Infection : Osteomyelitis, IBD and Atherosclerosis
Moderator: Josep Martin-Comin Co-Moderator: Helmut Sinzinger
1. Prosthetic Joint Infection (20 min) (C. J. Palestro)
2. Diabetic Foot Infection (20 min) (A. Signore)
3. Inflammatory Bowel Disease (20 min) (J. Martin-Comin)

4. Atherosclerosis (30 min) (H. Sinzinger)
 
Plenary Session
Wednesday September 22, 2010 (10:00 -11:30)
Inflammation & Infection : Novel Agents and Applications
Moderator: Victoria Soroa Co-Moderator: Mathew Thakur
1. Positron Emitters for Labeling Leukocytes (C. J. Palestro)
2. Gallium 68 (V. Kumar)
3. Molecular Imaging and Therapy of Inflammatory Atheromatous Disease (S. Srivastava)
4. Radiolabeled Vitamins (E. Lazzeri)
5. Molecular Imaging of Autoimmune Diseases (A. Signore)
6. Neutrophil Trafficking (C. J. Palestro)
7. Radiolabeled Stem Cells (M. Thakur) 


 

                                          

            The president, Victoria SOROA, is handing over the honorary plaque to the                                                      The plaque in detail
 former president Christopher PALESTRO during the ISORBE WFNMB Congress at Cape Town

 


Mathew THAKUR, the honorary president of ISORBE, riding an ostrich on a farm in Outshoorn on September 24, 2010

1st ISORBE Blood Cells Radiolabeling Certificate Course
DUBAI, UAE, November 17 - 19, 2009
Program Chair: Kutlan ÖZKER,   Program Co-Chair: Victoria SOROA
ISORBE Education Committee: Victoria SOROA, Josep MARTIN-COMIN, Kutlan ÖZKER, Christopher PALESTRO, Alberto SIGNORE, Helmut SINZINGER
IAEA Educational committee: Natesan RAMAMOORTHY

Country Coordinator: Jamila ALSUWAIDI, Assistant Coordinator: Sara BU HUMAID

 

             

ISORBE Education Committee: (from the left) Christopher Palestro, Kutlan Özker,
Victoria Soroa, Helmut Sinzinger

 
 

            

               Participants in the lecture room                                                               (from the left) Victoria Soroa, Jose Martin-Comin

                                                                                                                                                              

    

                                                                   Participants in front of the Dubai Health Authority Hospital


1st ISORBE Training Course, Dubai 2009 - Report
1. During the 14th Congress of the ISORBE which took place 26-28 March, 2009 in Antalya, Turkey, there was an international panel discussion on “Update on Design, Requirements and Regulations of a Radiopharmacy Facility in Relation to a Cell Labeling Facility” That session was the genesis of a consensus statement about the minimum requirements necessary for a cell labeling facility and minimum requirements for the training of staff. [Eur J Nucl Med Mol Imaging (2009) 36:1351-1352].

2. The course was organized by ISORBE and Dubai Health Authority–Dubai Hospital. This is the first certificate course organized by ISORBE.

3. ISORBE Education Committee was: Victoria Soroa, Helmut Sinzinger, Natesan Ramamoorthy, Christopher Palestro, Josep Martin-Comin, Kutlan Ozker. The Director of the 2009 Blood Cell Radiolabeling Certificate Course was Kutlan Ozker, the Local Coordinator was Jamila S AlSuwaidi and the Course Local Assistance was Sara Buhumaid.

4. The aim of the course was to train physicians and graduates of natural sciences or nuclear medicine technology who wish to work with radiolabeled blood elements. Priority was given to the candidates who are working in Nuclear Medicine Centers. The course was attended by 16 fully registered participants from 6 different countries. In addition there were many attendees from Dubai Hospital (physicians, pharmacists and technologists) and other local institutions for the didactic sessions.

5. The course was accredited by the Continuing Education Department of Dubai Health Authority as 13 Credit Hours (0755/09).

6. The course contained theoretical and practical sessions (a copy of the Scientific Program is attached).

7. It was also required that further practical work to be carried out at the workplace of individual participant as implementation of what have been learned during the course. The period of this on the job training was estimated to be about 3 months under the supervision of a tutor accepted by ISORBE. A total of 15 leukocyte labeling, 15 erythrocyte labeling and 5 platelet labeling (optional) were required from each participant in order to award the ISORBE Certificate for Radiolabeling of Blood Cells.

8. An evaluation of the course has been done during a round table discussion with all participants and the faculty. The participants expressed that the course was very helpful to them and showed a very high level of interest. The aim of the course was completely fulfilled by 3 working days of didactic class room hours in the mornings and practical in the afternoons. The participants found the link between the lectures and the practicals very helpful, and expressed in their words that there was an excellent communication between the participants and the faculty. Some participants required more practicals which will be implemented in the coming years.

Recommendations:
1. To run this type of the courses on a yearly bases at different regions.

2. To announce the course timely over the Americas, Africa, Europe and Asia to encourage participation from each region.

3. To have registration fees for the course. It was free of charge for the first year.

4. To have the cooperation of International Atomic Energy Agency for supporting participants from countries with limited financial resources.


5. Training on the radiolabeling of blood elements is directly related to the quality and safety of patients as well as safety measures to the workers. Updated training programs in this field will result in improved patient care and safety.

 

On the Job Training Feedback from Dubai Hospital WBC Radiolabeling:

No. Date done by Kit %Labeling Efficiency Supervisor
1 23-11-09 Mrs. Zainab BrainSpect HMPAO 78.9% Prof.Ozker
2 24-11-09 Ms. Najlaa LeucoScint  HMPAO 64.5% Prof.Ozker
3 25-11-09 Mrs. Zainab BrainSpect HMPAO 61.2% Prof.Ozker
4 6-12-09 Ms. Najlaa LeucoScint  HMPAO 82.3% Prof.Ozker
5 7-12-09 Mrs. Zainab LeucoScint  HMPAO 71% Prof.Ozker
6 8-12-09 Ms. Najlaa BrainSpect HMPAO 88.3% Prof.Ozker
7 9-12-09 Mrs. Samera LeucoScint  HMPAO 77.6% Prof.Ozker
8 29-12-09 Mrs. Zainab LeucoScint  HMPAO 77.3% Dr.Suhaili
9 30-12-09 Ms. Najlaa LeucoScint  HMPAO 81.4% Dr.Suhaili
10 7-01-10 Mrs. Zainab LeucoScint  HMPAO 70.2% Dr.Suhaili
11 14-01-10 Ms. Najlaa LeucoScint  HMPAO 81.8% Dr.Suhaili
12 21-01-10 Mrs. Zainab LeucoScint  HMPAO 66% Dr.Suhaili
13 11-02-10 Ms. Najlaa LeucoScint  HMPAO 81.4% Dr.Suhaili
14 18-02-10 Mrs. Zainab LeucoScint  HMPAO 75.3% Dr.Suhaili
        mean=75.5%  


























The candidates who successfully completed the formal training and internship terms were awarded by ISORBE “Certificate on Radiolabeling of Blood Cells”.

Najlaa Certificate.pdf

Zainab Certificate.pdf

Hana Hourani Certificate.pdf

SPONSORS: Dubai Health Authority; Covidien, The Netherlands; Medi-Radiopharma, Hungary; Al Zahrawi Medical Supplies LLC, Dubai.
HMPAO kits are gifts from Medi-Radiopharma, In-111 is a gift from Covidien.



ISORBE Plenary Session on Infection/Inflammation at the XXII ALASBIMN Congress

CARTAGENA, Colombia, November 6, 2009
"Molecular imaging atherosclerosis, thrombosis, inflammation, infection"
Organisation: Victoria SOROA
Chairmen: M. PABÓN, M. DEL HUERTO, O. VÉLEZ, A. LLAMAS
Lectures by: Victoria Soroa, J. Buscombe, S. Srivastava, K. Hazra, A. Llamas, J. Martin-Comin, N. Prandini, M. Thakur, H. Sinzinger, A. Signore

 

 

 In Cartagena the Presidium anonymously elected Prof. Mathew THAKUR as the recipient of the first McAfee Medal   

  
 

Prof. Mathew THAKUR was awarded the Mc Afee Medal
 


14th ISORBE Congress  

ANTALYA, Turkey, March 26 - 28, 2009
Congress President: Firat GÜNGÖR

Scientific Committee: Hatice DURAK, Binnur KARAYALCIN, Josep MARTIN-COMIN, Wim OYEN, Kutlan ÖZKER, Christopher PALESTRO, Alberto SIGNORE, Helmut SINZINGER, Victoria SOROA, Mathew THAKUR, Mustafa ÜNLÜ 

 

 

 

Meeting announcement




 Lecture room at the 14
th ISORBE Congress
 

 

 

              
 

The President of the Meeting Firat GÜNGÖR together with ISORBE President Victoria SOROA and
the former Presidents Helmut SINZINGER, Christopher PALESTRO and Josep MARTIN-COMIN



 


 

Participants of the 14th ISORBE Congress



Nuclear Medicine Methods for the Study of Inflammatory Processes and Infection
under the patronage of ISORBE
GRONINGEN, The Netherlands, May 22 - 23, 2008

Organisation and Scientific Committee: O.C. BOERMAN, Rajo DIERCKX, Wim J.G. OYEN, Alberto SIGNORE

Local Organizing Committee: A.M.J. Paans, J. Pruim, M.G.G. Sturkenboom, G.J. de Voogd, E.F.J. de Vries, A. van Waarde
Lectures by: O.C. Boerman, H.H. Boersma, J. Buscombe, M. Chianelli, R.A. Dierckx, J.J.A.M. van den Dungen, O. Israel, F. Jamar, E. Lazzeri, P.G.M. Maathuis, G. Malviya, J. Martin-Comin, J. Meller, W.J.G. Oyen, J. Pruim, M. Roca, A. Signore, H.G. Sprenger, E.F.J. de Vries, M.M. Welling, C. van de Wiele



 


 



 



 


 


13th ISORBE Congress at the ALASBIMN Conference

SANTA CRUZ, Bolivia, December 1, 2007 

Organisation: Victoria SOROA
Chairmen: Christopher PALESTRO, John BUSCOMBE, Kishor SOLANKI, Vivian PEREYRA, Silvia CASTIGLIA, Karina M. FERNANDEZ

Lectures by: C. Palestro, J. Martin-Comin, H. Sinzinger, J. Vilar, V. Kumar, K. Solanki, J.L. Crudo, J. Buscombe, Victoria Soroa, M. Thakur


 

                                                                    

 

  

 

Participants of the 13th ISORBE Congress



ISORBE at the World Congress of Nuclear Medicine and Biology
SEOUL, South Korea, October 22, 2006
"Infection and Inflammation Imaging Around the World"
Organisation:
Christopher PALESTRO, Mathew THAKUR

Lectures by: M. Sathekge, J. Martin-Comin, C. Palestro, M. Thakur, H. Sinzinger, M. Dettke, Victoria Soroa


ISORBE Pre-EANM Symposium
ATHENS, Greece, September 30, 2006 
"Imaging, infection and atherosclerosis - from basic science to clinical practice"
Organisation:
Alberto SIGNORE, Josep MARTIN-COMIN
Chairmen: John BUSCOMBE, Alberto SIGNORE, Christopher PALESTRO, Josep MARTIN-COMIN, Mathew THAKUR, Helmut SINZINGER

Lectures by: J. Meller, D. Rubello, C. Palestro, J.C. Alonso, A. Chiti, J. Buscombe, N. Prandini, J. Martin-Comin, S. Kyriakongonas, I. Carrio, A. Signore, D.L. Kraitchman, G. Lucignani


 

  
 

ISORBE Symposio at the ALASBIMN Conference
PUNTA DEL ESTEe, Uruguay, December 4, 2005
Organisation: Javier VILAR

Chairmen: Horacio AMARAL, Victoria SOROA, Eduardo NOGUERA, Juan José LOPEZ

Lectures by: M. Thakur, N. Nin, C. Palestro, J. Buscombe, H. Sinzinger, Victoria Soroa, J. Martin-Comin


12
th ISORBE Congress

 VILLIGEN, Switzerland, September 1 - 3, 2005
Organisation: Johannes T. LOCHER
Lectures by: J. Martin-Comin, A. Signore, C. Palestro, M. Thakur, J. Buscombe, A. Annovazzi, H. Sinzinger, Grazyna Sobal, W. Oyen, K. Strobel, A. Gratwohl


 

    

 

Meeting Program
 

 

        

  

Prof. Johannes LOCHER, who unfortunately died too early on March 6th 2007 after sudden heart attack, giving his talk in Villigen

 

                        Members of the presidium and meeting participants after the election at Villigen
(left to right: C. D'Alessandria, J. Martin-Comin, M. Chianelli, A. Signore, W. Oyen,
C. Palestro, H. Sinzinger, J. Buscombe, N. Prandini, M. Thakur, Grazyna Sobal)


 

ISORBE Scientific Meeting at the EANM Conference
HELSINKI, Finland, September 4, 2004

Organisation: Wim OYEN
Lectures by: J. Buscombe, J. Martin-Comin, C. Palestro, M. Thakur, H. Sinzinger, A. Signore, M. Larikka, K. Kairemo, W. Oyen, and K. Stumpe


 


11th ISORBE Congress

COIMBRA, Portugal, April 11 - 12, 2003

Congress President: Joao Manuel PEDROSO DE LIMA
International Scientific Committee: Christopher PALESTRO, Alberto SIGNORE, Helmut SINZINGER, Mathew THAKUR
Organizing Committee: Margarida RODRIGUES, Ana FERRER-ANTUNES, Christina BAETA, Jorge ISIDORO, Janine CORREIA

Lectures by: J. Martin-Comin, W. Oyen, C. Palestro, J.M. Pedroso de Lima, A. Pestema, J. Prats, Margarida Rodrigues, S. Semedo, A. Signore, H. Sinzinger, Grazyna Sobal, K. Solanki, M. Thakur

 

 

 

  Part of the audience during the ISORBE Meeting in the historical lecture room

at the OldUniversity of Coimbra


 

ISORBE Post-Congress Meeting WFNMB & ALASBIMN Congress
 SANTIAGO, Chile, October 5, 2002

"ISORBE, on infection, inflammation & thrombosis"

Organisation: Mathew THAKUR, Margarida RODRIGUES

Chairmen: Alberto SIGNORE, Vikram LELE, Daya Kishore HAZRA, Christopher PALESTRO
 

This symposium in Chile was dedicated to Prof. Wolfgang BECKER, the Past President of ISORBE (1997 - 1999), who passed away on May 18th, 2002. His contributions to the field of imaging infection/inflammation and to ISORBE were extensive.

 

The History of Blood Cell Labeling 1976 - 2001

The landmark events in the history of the International Society of Radiolabeled Blood Elements (ISORBE) can be traced back to more than two decades ago at the MRC Cyclotron Unit, Hammersmith Hospital in London, U.K, when Drs. John McAfee who then was at State University of New York, Syracuse, was on sabbatical leave at MRC Cyclotron Unit (July to December 1974) and Mathew Thakur surveyed more than 50 soluble and particulate agents to label human white blood cells (WBCs) with a gamma emitting radionuclide.
 


Drs. John McAfee and Mathew Thakur more than 20 years ago, when they were working together at the Hammersmith Hospital, London, UK

Bombarding a large number of metal ions or their compounds in a fixed energy 30" diameter cyclotron, Mathew Thakur prepared such gamma emitting radionuclides as Fe-52, Zn-62, Rb-81, Pb-203, I-123, In-111 and Ga-67 and converted them into a variety of suitable chemical forms for WBC labeling. Using a generator produced Tc-99m several other compounds were also prepared. These were then examined for labeling white blood cells separated from plasma. The work went on non-stop for full six months, during which time each of them donated blood every other working day. Consuming fatty meals or even coffee or tea with cream 30 - 45 minutes prior to drawing blood was prohibited for it retarded blood sedimentation.

It was then Mathew Thakur's turn to go on sabbatical (June 1975 - May 1976) to Dr. Michael Welch's group at Mallinckrodt Institute of Radiology (MIR), Washington University, St. Louis. There he choose to work with In-111-oxine which appeared to be a most promising agent. It was in St. Louis where the first abscess images in dogs were obtained. Furthermore, platelets have been labeled as well with In-111-oxine and experimental deep venous thrombosis was detected by scintigraphy. The facility was excellent and the cooperation of Drs. R.E. Coleman, M.J. Welch and their colleagues was outstanding. "It turned out to be the most exciting and highly successful year of my career. Every experiment I did at St. Louis was successful. I wish this could happen all the time,"  recalls Mathew Thakur.
The hard work resulted in some important publications as for instance Indium-111 labeled platelets: Studies on preparation and evaluation of in vitro and in vivo function from the authors M.L. Thakur, M.J. Welch, H. Joist and R. E. Coleman published in Thromb. Res.4, 345-357 in 1976, or Indium -111- labeled leukocytes for the localization of abscesses: preparation, analysis, tissue distribution, and comparison with Gallium-67-citrate in dogs from M.L. Thakur, RE. Coleman and M.J. Welch, published in the Journal of Laboratory and Clinical Medicine, 89: 217 - 228 in 1977.

Dr. Thakur then went back to Hammersmith and worked with Professor Ford at the University of Manchester and labeled lymphocytes with In-111-oxine. At Hammersmith, using In-111-oxine labeled WBC, he worked with Dr. J.P. Lavender and by the end of 1976 they studied 20 patients with known abscesses or with fever of unknown origin. Using In-111 labeled lymphocytes they also studied a few patients with Hodgkin's disease. The results have been published in the British Medical Journal (2: 797-799, 1977) by the authors J.P. Lavender, J.M. Goldman, R.N. Arnot and M.L. Thakur under the title Kinetics of Indium-111 labelled lymphocytes in normal subjects and patients with Hodgkin's disease.

In February 1977 Mathew took a position with Dr. Alexander Gottschalk in the Department of Radiology at Yale University School of Medicine and worked with a cardiologist, Drs. B. Zaret and A. Riba, demonstrating the application of In-111 labeled platelets in detecting experimental bacterial endocarditis and coronary artery thrombosis. Twenty patients with known myocardial infarction were also studied with In-111-WBC and infarcted myocardium was successfully delineated. Imaging experimental infective endocarditis with Indium-lll-labeled blood cellular components (Circulation 59: 336-343, 1979) and Imaging experimental coronary artery thrombosis with Indium-111 platelets (Circulation 60: 767-775, 1979) from the authors A.L. Riba, M.L. Thakur, A. Gottschalk, V.T. Andriole and B.L. Zaret are publications from this period.

By this time, the Diagnostic Isotopes had already begun to produce In-111-oxine for limited supply within the USA. Supported by Diagnostic Isotopes, Drs. Thakur, Gottschalk and Zaret organized the first symposium on radiolabeled cellular blood elements which was held in November 1979 in New York. This generated a tremendous impetus amongst the investigators in a variety of disciplines throughout the world. By early 1980, at one time there were as many as 600 Investigational New Drug (IND) applications filed with the USA Food and Drug Administration (FDA). In 1985 In-111-oxine was approved by the FDA as a low risk substance.
In 1982, NATO provided nearly US$ 40.000,- to hold an advanced study institution in Maratea, Italy, for two weeks. The meeting held in an isolated hotel looking the Mediterranean permitted to researchers corning from all over the world, to discuss deeply both, the basic principles and the clinical applications of radiolabeled blood elements; it could probably be considered the starting point for the widespreading of clinical applications. Since then, once in every two or three years an international symposium on radiolabeled blood elements is held. In addition there have been pre- or post-congress meetings connected with the EANM-Conferences, such as those in Dusseldorf, 1994 and in Copenhagen, 1996. The chronology of these events provided in the time-table.

When Mathew Thakur visited Helmut Sinzinger in Vienna in 1988 they got together in a rural style restaurant named D'Rauchkuchl to discuss the organization of the forthcoming meeting and they also talked about their experience in labeling blood cells. Among other issues they discussed was the number of scientists working in the field of labeled blood cells. The number was increasing exponentially, so they decided to found a Society dealing with this topic. During the 5th International Symposium on Radiolabeled Blood Elements in 1989 in Vienna the International Society of Radiolabeled Blood Elements (ISORBE) was established and was registered in Vienna on August 20th, 1990.
 

Abb. label ISORBE

This sign has been created by Ernst Havlik, a physicist at the Department of Nuclear Medicine in Vienna, to represent ISORBE


In 1992 Mathew Thakur received the Paul Aebersold Award at the SNM Annual Meeting for his outstanding achievements in Nuclear Medicine. Mathew has an outstanding ability to bridge the gap between basic chemistry and its successful application to clinical problems the very thing for which this award is given wrote David A. Goodwin, Chief of Nuclear Medicine, Palo Alto, CA. Among many others receiving recognition by Peers for their contribution to the field were John McAfee, Jose Martin-Comin and Helmut Sinzinger who was awarded twice in 1992 for his work in the field of labeled blood elements. The first was the CIS Jean Debiesse Award which he received during the EANM-Congress in Lissabon for the work on radiolabeling of low-density lipoproteins for the imaging of atherosclerosis. The second one was handed over in Paris in September for the clinical research on Evidence for increased vascular monocyte uptake in patients with heterozygous familial hypercholesterolemia in-vivo during the International Angiology Conference.

One day in June late in the evening the phone rang in Helmut Sinzinger's office; Mathew Thakur called from the States and asked him whether he would be ready to become the next president. At the 6th International Symposium of the ISORBE in November 1992 in Barcelona, Spain, Helmut Sinzinger was elected to become the second President of the society for the next three years. As the Secretary for ISORBE John McAfee had taken the membership administration task in which he did a superb job. The logo of the Meeting (the organizers offered a keyholder to all speakers) was the basis for the ISORBE logo, finally designed by Ernst Havlik. The first draft of it was designed together with Mathew Thakur.

During the period of Helmut Sinzinger's presidency the Society started to provide the members for the first time with Newsletters which were published at irregular intervals.

Since its initiation 20 years ago, the work in the field has continued to grow. On Saturday, the 20th of August 1994, during the European Association of Nuclear Medicine Congress in Düsseldorf, Germany, the Society organized for the first time a pre-congress meeting where the latest findings on imaging inflammation and vascular lesions were presented. This was followed by an extremely lively round table discussion. In the evening all the members of the Board of Directors attending the EANM-conference met for dinner in a delightful fish-restaurant in the center of Düsseldorf and talked on some details about the forthcoming ISORBE-meeting in 1995 at the Yale University, New Haven, USA, to be organized by Mike Ezekowitz, his colleagues and the helping hand of Paulette Trent.

In the course of the Meeting at Yale University in New Haven 1995 Jose Martin-Comin was elected anonymously to become the third president of the ISORBE.

Martin-Comin hosted a dinner for the Board of Directors, for it was the time to talk about the 8th International Congress of the ISORBE in Rome more in detail.

The Meeting in Rome was organized by Alberto Signore, the ISORBE Secretary at that time. He was doing an outstanding job for the Society during the past two years presenting the Newsletters with valuable scientific contributions, paper banks and information on forthcoming events, available to all members at regular intervals. The publication of suggested methodologies for blood cell labeling and the regular appearance of ISORBE News in the European Journal of Nuclear Medicine are the closest projects.

The scientific program in Rome in May 1997 was highly educational professionally, beneficial and socially enjoyable. Alberto managed to invite most prominent investigators in the field of atherosclerosis and thrombosis (Russel Ross, Valentin Fuster) and to attract a large number of abstracts. The ISORBE-family of researchers had an exciting week in Rome.

Today, more than 20 years later, labeled blood cells/elements examinations are routinely practiced in most Nuclear Medicine Departments. The clinical impact of these examinations on patients management is quite important in different pathologies. Nevertheless, the research for better, more specific, simple and safe agents and techniques continues and the challenge of ISORBE is to contribute to this progress.
 

AWARDS*:
Premio JEN-1986 concedido por la Junta de Energia Nuclear al trabajo: "Utilidad de la gammagrafia con leucocitos-111In-oxina en el brote agudo de la enfermedad inflamatoria intestinal" R. Villa, J. Martin-Comin, J.J. Gine, T. Casanovas, A. Ybern y M.A. Gasull. Palma de Mallorca, Junio de 1986

Accesit al mejor trabajo publicado en la Revista de la S.E.M.N.: "Marcaje de leucocitos con 99mTc-HMPAO. Estudio metodologico" M. Roca, J. Mora, M.L. Prat, J. Daumal, C. de la Fuente y J. Martin-Comin. Rev. Esp. Med. Nuclear 8: 3-7, 1989.

Paul Aebersold Award for the scientific work in labeling blood cells, monoclonal antibodies and peptides at the SNM Annual Meeting in 1992 for Mathew Thakur.

CIS Jean Debiesse Award for the work on radiolabeling of low-density lipoproteins for the imaging of atherosclerosis during the EANM-Congress in 1992 for Helmut Sinzinger.

Helmut Sinzinger's presentation "Evidence for increased vascular monocyte uptake in patients with heterozygous familial hypercholesterolemia in vivo“ was awarded during the International Angiology Conference in September 1992. 
*This is just a selection, not a complete list
 
EVENTS
1st Meeting New York 1979:
 
Following Mathew Thakur's information this meeting was attended by about 60 investigators from the USA and Canada. It was organized by Drs. Thakur, Gottschalk and Zaret and fully supported by the late Mr. James Finn, president of Diagnostic Isotopes, NJ, the company which made In-111-oxine commercially available first. The company was later bought by Medi-Physics, which paid for the publication of the first book on the subject, edited by Thakur and Gottschalk. The impetus generated by the success of this meeting prompted Mathew Thakur to organize the first International Symposium on the subject in 1982. This meeting is frequently referred as the NATO- or the Maratea-meeting.


2nd Meeting Maratea 1982: 
 
This meeting, for a variety of reasons, has provided the most vivid memories to most of its participants. Despite a few unpleasant events, mostly related to the warm tropical climate in Maratea, a tiny village at the west coast of Italy, approximately 100 miles from Naples. This ten days meeting was most enjoyable, socially as well as professionally. Many participants of this meeting became life-long friends, and it may not be an exaggeration to say that it is that friendship and the loyalty to the subject matter of the meeting led to the formation of ISORBE. A large proportion of the funding for the meeting was provided by NATO, although its organizers gratefully acknowledged the support made available by Medi-Physics, Amersham International, Mallinckrodt Inc. and Beckman International. Mathew Thakur, the director, with his equally able co-directors Max Hardeman and Michael Ezekowitz, invited many prominent speakers of international reputation to give plenary lectures and encouraged many newcomers to attend the meeting.


Helmut Sinzinger during his lecture

111Indium has been established as the radioisotope of choice for the study of platelet and granulocyte kinetics. Mike Ezekowitz was presenting a movie in which his technician Eileen O. Smith was showing their optimized procedure for labeling of platelets. An intensive and sometimes hot discussion was surrounding the optimal labeling methodology for platelets and white blood cells. The scientific program not only included didactic lectures and scientific presentations in a large theater of a hotel on the top of a steep hill, 100 feet above a clean, sunny beach but also of open ground discussions during pizza parties, soccer- and volleyball games, during fishing trips and a trip to historical Pompeii. The wasps and ants were also friendly: they frequently followed the guests into their rooms, their beds, the dining hall and sometimes, even into the sandwiches of most affectionate people like Eva Jäger. When the elevator failed, we climbed nearly 150 steps to the hotel from the beach. When David Goodwin accidentially lost his wallet in the sandy base of the 15 foot deep, clear blue ocean, we retrieved it. When John McAfee lost his only pair of glasses during a boat trip, we found them. The Italian wine regularly served at dinner time showed its presence in the stomaches of a few, but most did not mind it. Food normally was served late and cold, but only a few, as eg Vera Fitscha, managed to lose their appetite for it. The climate was perfect for "funghi porcini", which we were enjoying repeatedly. It was the first time the crowd discovered how avid a soccer player, Jose Martin-Comin, was and how charming Wolfgang Becker looked even then without a beard. Mathew Thakur pretended to be busy for most of the time but managed to play basketball with the sleeves of his shirt rolled down to his wrists. And so on! What a great meeting it was!

List of participants:
W. Adam, Germany; S. Aydar, Turkey; P.N. Badenhorst, RSA; W. Becker, Germany; D.M. Bellotto, Canada; L. Boutal, UK; F. Brady, UK; M. Budabin, USA; R. Claessens, The Netherlands; M.E. Clay, USA; L. Crawford, USA; E. Deisenhammer, Austria; E. Dienstl, Austria; J.G. Doorenspleet, The Netherlands; A. Driedger, Canada; F. Eckhard, Germany; M. Ekman, Sweden; D. English, USA; G.J. Easing, The Netherlands; J. Fehr, Switzerland; P. Fitscha, Austria; L.A. Forstrom, USA; G.F. Fueger, Austria; P. Gerundini, Italy; F. Gokan, Turkey; G. Grimfors, Sweden; A. Grossi, Italy; A.A. Guerrero, Spain; U. Guven, Turkey; R. Haznedar, Turkey; J. Hiltunen, Finland; S. Hoory, USA; M. Horvath, Hungary; S.E. Lace, UK; Eva Jäger, Austria; Ch. Kessler, Germany; J.B. Laidler, UK; P. Lavender, UK; J. Le Cloirec, France; A. Levasseur, Canada; F. Lomena, Spain; F. Loumas, Australia; C. Lundburg, Sweden; J. Martin-Comin, Spain; B.H. Mock, USA; A. Moisan, France; D.D. Munjal, USA; S.N. Nielsen, Denmark; D. Orkide, Turkey; C.P. Page, UK; M.A. Peters, UK; D. Picard, Canada; C. Piera, Spain; C. Pozzilli, Italy; M. Quastel, Israel; J.W. Rasmussen, Denmark; C. Raymonde, Canada; M. Roca, Spain; J.-E. Ryser, Switzerland; A. Signore, Italy; H. Sinzinger, Austria; E.O. Smith, USA; S. Tassmari, USA; M. Thakur, USA; H.M. Towler, UK; K. Uno, Japan; P.J. Voogt, The Netherlands; H.W. Wagner, USA; A. Warbick-Cerone, Canada; Y.G. Zorbas, Greece
 

3rd Meeting Bloemfontein 1986:




Anthon du P. Heyns, his wife and Wolfang Becker enjoying dinner



In a memorable journey we were taken by our hosts tour to the Krueger National Park. Starting close to midnight (i.e. 4:00 a.m) we were driven with jeeps from Bloemfontein to the park. Immediately at the entrance we were greeted by a family of lions, later on seeing an impressive picture of buffalo herd, elephants, giraffes, antilopes, hyenas. and many others. A group of monkeys we were disturbing during their lunch time sitting on and around trees. The overnighting in the camps including the outdoor grilling were unique events as well. After this unforgettable trip some of us were presentmg lectures at different places in South Africa, among them in Durban and Capetown. We got an impression on the political situation of South Africa for it was the period of time where they started seriously to stop the ethnical separation.

 


Our South African colleagues during the trip through Krueger National Park


List of participants:
P.N. Badenhorst, Bloemfontein, RSA; G.M.B. Berger, Rondebosch, RSA; N. Chetty, Johannesburg, RSA; P.J. Commerford, Observatory, RSA; E.B. Dowdle, Observatory, RSA; A. Eldor, Jerusalem, Israel; M.D. Ezekowitz, New Haven, USA; R.C. Franz, Pretoria, RSA; W. Gevers, Observatory, RSA; R.S. Hanson, La Jolla, USA; M.R. Hardeman, Amsterdam, NL; L.A. Harker, La Jolla, USA; A. du P. Heyns, Bloemfontein, RSA; E.J. Immelman, Observatory, RSA; H.F. Kotze, Bloemfontein, RSA; R. Lijnen, Leuven, Belgium; M.G. Lotter, Bloemfontein, RSA; J.F. Mustard, Hamilton, Canada; R.D. Neirinckx, Buckinghamshire, U.K.; A.M. Peters, London, UK; H. Pieters, Bloemfontein, RSA; C. Rosendorff Parktown, RSA; H. Sinzinger, Vienna, Austria; J. Vermylen, Leuven, Belgium; P. Wessels, Bloemfontein, RSA
 

4th Meeting Cologne 1987:



Christoph Kessler, a neurologist who recently moved to Lübeck and just preparing his Dozent (associate professorship), was ambitiously organizing a conference aiming in particular to assess the role of platelet labeling in carotid artery disease.

List of Participants:
J. Bannenberg, Amsterdam, NL; W. Becker, Würzburg, Germany; M. Brenner, Homburg/Saar, Germany; G.V. Desir, New Haven, USA; M.I.C. Dewanjee, Rochester, USA; A.J. Funke Kupper, Amsterdam, NL; D.A.J. Galvin, London, UK; M. Goldman, Birmingham, UK; M.R Hardeman, Amsterdam, NL; R.A. Harper, London, UK.; W.D. Heiss, Köln, Germany; H. Henningsen, Heidelberg, Germany; M. Hipp, Köln, Germany; V. Hossmann, Köln, Germany; Ch. Kessler, Köln, Germany; T. Kniffert, Berlin, Germany; J.P. Lavender, London, U.K; H. Louwes, Gröningen, NL; J. Martin-Comin, Barcelona, Spain; A.C. Meek, London, UK; G. Modder, Köln, Germany; A. Moisan, Rennes, France; G. Pawlik, Köln, Germany; J.N. Petrovici, Koln, Germany; R Reuther, Heidelberg, Germany; E.B. Ringelstein, Aachen, Germany; M. Rotsch, Heidelberg, Germany; E. Schell-Frederick, Köln, Germany; H. Sinzinger, Vienna, Austria; J.R. Stratton, Seattle, USA; M.L. Thakur, Philadelphia, USA; F.W.A. Verheugt, Amsterdam, NL; P. Voosen, Köln, Germany.

 5th Meeting Vienna 1989:

The 5th International Symposium in September 1989 in Vienna was organized by Helmut Sinzinger with the helping hand of Susi Granegger, together with Mathew Thakur. There have been nearly hundred participants from over Europe, some came from the United States, and even from South-Africa and Japan. The new findings presented during the conference have been lively discussed. The atmosphere was really familiar, the participants had much fun during the trips, for instance to the Monastery Klosterneuburg and to the oldtimer car museum in Stockerau, which is owned by our colleague Gerry Brandstetter, the Head of the Department of Internal Medicine and Director of the county hospital in Stockerau.
 


Gerry Brandstetter in one of his oldtimers at the museum in Stockerau

List of participants:
N. Arimizu, Chiba, Japan; Ch. Auinger, Vienna, Austria. P.N. Badenhorst, Bloemfontein, RSA; K Bakos, Praha, Czechoslovakia; W. Becker, Erlangen, Germany; R Beer, Marburg, Germany, P.C.L. Beverley, London, UK; P. Blauenstein, Villigen, Switzerland; F. Bock, Vienna, Austria: M. Bock, Manchester, UK; A. Bockisch, Bonn, Germany; H. Brenner, Vienna, Austria; M. Chianelli, Rome, Italy; P. Chiba, Vienna, Austria; B. Collet, Rennes, France; M. DeRoo, Leuven, Belgium; M.K Dewanjee, Miami, USA; D. Dodig, Zagreb, Yugoslavia; M.D. Ezekowitz, New Haven, USA; RA. Fawwaz, New York, USA; T. Feichtenschlager, Vienna, Austria; P. Fitscha, Vienna, Austria; J. Fortynova, Praha, Czechoslovakia; J. Hancevic, Zagreb, Yugoslavia; M.R. Hardeman, Amsterdam, NL; P.H. Hasler, ViUigen, Switzerland; A.duP. Heyns, Bloemfontein, RSA; D.B. Hocken, London, U.IC; R Hofer, Vienna, Austria; H. Hoffken, Marburg, Germany; K. Itoh, Sapporo Japan; D. Ivancevic, Zagreb, Yugoslavia; H. Jackson, Manchester, UK; J. Johansen, Odense, Denmark; K Joseph, Marburg, Germany; C. Kessler, Lübeck, Germany; G. Kleinpeter, Vienna, Austria; Ch. Kolbl, Vienna, Austria; K.F. Kotze, Bloemfoatein, RSA; A. Kroiss, Vienna, Austria; K. Lange, Marburg, Germany; J. Lecloirec, Rennes, France; N. Colas Linhart, Paris, France; M. Livakovic, Zagreb, Yugoslavia; J.T. Locher, Aarau, Switzerland; F. Lomena, Barcelona, Spain; O. Loreal, Rennes, France; G. Lupattelli, Perugia, Italy; J. Marienhagen, Erlangen, Germany; J. Martin-Comin, Barcelona, Spain; F. Mata, Palma de Mallorca, Spain; J.G. McAfee, Washington, USA; C.N. McCollum, London, UK; A. Moisan, Rennes, France; L. Mortelmans, Leuven, Belgium; Ch. Müller, Vienna, Austria; I. Novak-Hofer, Villigen, Switzerland; P. Oehr, Bonn, Germany; Z.K. Oster, Stony Brook, USA; G. Perneczky, Vienna, Austria; H. Pieters, Bloemfontein, RSA; B.S. Poulsen, Odense, Denmark; B. Pramsohler, Villach, Austria; F. Rauscha, Vienna, Austria; M. Roca, Barcelona, Spain; K.G. Schmidt, Odense, Denmark; K. Scholz, Villach, Austria; P.A. Schubiger, Villigen, Switzerland; A. Schwarz, Frankfurt, Germany; K.L. Sharma, Maachester, UK; A. Signore, Rome, Italy; K Sinzinger, Vienna, Austria; Eva Strobl-Jäger, Vienna, Austria; J. Stuyck, Leuven, Belgium; M.L. Thakur, Philadelphia, USA; L. Toujas, Rennes, France; J.K. Turner, Fremantle, Australia; K. Uno, Chiba, Japan; Irene Virgolini, Vienna, Austria; M. Vopatova, Praha, Czechoslovakia; G. Weidlich, Vienna, Austria; V. Weiler, Vienna, Austria; K. Weiss, Vienna, Austria; P. Winter, Bonn, Germany
 

 6th Meeting Barcelona 1992:

            


The symposium in Barcelona, the best and largest one up to this time, organized by Jose Martin-Comin and his coworkers in November 1992, was attended by about 130 investigators from 20 different countries (among them 14 European countries). A total of 87 research papers were presented (General 6, Peptides 1, Platelets 22, Leucocytes 29, Erythrocytes 2, Monoclonal Antibodies 12, IgG 8, others 7) and ample time was provided for after session and round table discussions. Overall, it was clearly evident that the merger of new technologies has presaged an exciting period in the field of diagnostic imaging with radiolabeled blood components. The whole meeting, including the social events, such as the trip to the Codorniu sparkling wine cellar in the mountains and the wonderful mediterranean atmosphere and pleasant sunny climate of Barcelona have been very well accepted by the participants. The dinner for the Board of Directors in the restaurant Set Portes at the port was an endless atherogenic journey through the Catalan cuisine.

 


Some of the colleagues from the Organizing Committee in Barcelona

List of participants:
V. Alvarez, Princeton, USA; P. Angelberger, Vienna, Austria; P. Badenhorst, Bloemfontem, RSA; M.T. Bajen Lazaro, Barcelona, Spain; J. Banzo Marraco, Zaragoza, Spain; A. Baroli, Novara, Italy; P. Bass, Barcelona, Spain; A. Bastos-Lima, Porto, Potugal; W. Becker, Erlangen, Germany; P. Bernard, Marseille, France; M. Bernardo- Filho, Rio de Janeiro, Brazil; M.H. de Bois, Leiden, NL; J. Buscombe, London, UK; J. Caix, Bordeaux, France; I. Carrio, Barcelona, Spain; F. Casals, Barcelona, Spain; M. Castell Fabrega, Barcelona, Spain; A. Catafau, Barcelona, Spain; M. Chianelli, London, UK; F. Corstens, Nijmegen, NL; M.I. Cotta Cardoso, Porto, Portugal; D.J. Coughin, Princeton, USA; I. Couret, Montpellier, France; C. de Labriolle-Vaylet, Paris, France; M. de Sequera Rahola, Sta. Cruz de Tenerife, Spain; R. Dean, Londonderry, USA; M.K. Dewanjee, Miami, USA; F.M. Domenech Tome, Barcelona, Spam; M.D. Ezekowitz, New Haven, USA; M.R. Fernandez Espina, Barcelona, Spain; F. Güngör, Izmir, Turkey; A.M. Forster, Bucks, UK; J. Fortunato, Porto, Portugal; M. Fraile Lopez-Amor, Barcelona, Spain; A. Furno, Bologna, Italy; A. Garcia, Barcelona, Spain; A. Garcia Burillo, Barcelona, Spain; J.R. Garcia Garzon, Barcelona, Spain; J.M. Gonzalez, Baroelona, Spain; D.A. Goodwin, Palo Alto, USA; J.L. Gordon, Oxford, UK; Susanne Granegger, Vienna, Austria; R. Herranz, Barcelona, Spain; M. Huguet Panella, Barcelona, Spain; V. Ivanceviv, Göttingen, Gemany; B. Jansson, Huddinge, Sweden; Daya K. Hazra, Agra, India; R. Kinne, Erlangen, Germany; K.F. Kotze, Bloemfontein, RSA; A. Kroiss, Vienna, Austria; G. Landonio, Milano, Italy; D. Lasa, Madrid, Spain; J. Locher, Aarau, Switzerland; F. Lomena Caballero, Barcelona, Spain; J. Looman, Petten, NL; K. Louwes, Groningen, NL; L. Lusiani, Castelfranco, Italy; L. Mairal Padro, Barcelona, Spam; M.J. Marek, Albuquerque, USA; J. Martin-Comin, Barcelona, Spain; M.L. Martinez Pueyo, Madrid, Spain; F. Mata, Palma de Mallorca, Spain; M. Minoves Pont, Barcelona, Spain; A. Moisan, Rennes, France; J. Mora Salvado, Barcelona, Spain; M. Moragas, Barcelona, Spain; L. Mortelmans, Malvern, USA; M.A. Muxi, Barcelona, Spain; J. Pavia, Barcelona, Spain; A.M. Peters, London, UK; C. Piera, Barcelona, Spain; F. Pons, Barcelona, Spain; N. Prandini, Ferrara, Italy; M.L. Prat Elias, Barcelona, Spain; E. Prats Rivera, Zaragoza, Spain; L. Ramirez, Barcelona, Spain; M. Ramos, Barcelona, Spain; M. Ramos Marquez, Barcelona, Spain; Y. Ricart, Barcelona, Spain; E. Riera, Barcelona, Spain; M. Roca, Barcelona, Spain; G.M. Sacchetti, Novara, Italy; M. Sala Suarez, Barcelona, Spain; C. Sampson, Cambridge, UK; T. Schaible, Malvern, USA; G.R. Schinella, La Plata, Argentina; K.G. Schmidt, Odense, Denmark; M.I. Segarra Merino, Barcelona, Spain; J. Setoain, Barcelona, Spain; F.J. Setoam Perego, Barcelona, Spain; K. Seybold, Aarau, Switzerland; A. Signore, Rome, Italy; H. Sinzinger, Vienna, Austria; S. Solanski, Cambridge, UK; B. Soriano Borras, Barcelona, Spain; F. Spinelli, Milano, Italy; S.C. Srivastava, New York, USA; M.A. Sweetlove, Bloemfontein, RSA; M.L. Thakur, Philadelphia, USA; G. Torres, Barcelona, Spain; K. Uno, Chiba, Japan; C. Van Neron, Leuven, Belgium; Irene Virgolini, Vienna, Austria; I.M. Wedebye, Tommerup, Denmark; R .Weiner, Farmington, USA
 

7th Meeting New Haven 1995:

After some economic difliculties at the beginningof the organizing work for the 7th Symposium of the ISORBE, Michael D. Ezekowitz has been very successful and the participants joined a very interesting meeting again. As a matter of fact, the number of American participants was quite high, on the other hand the one of Europeans rather low. It has been a pleasure to visit the old historical buildings at the Yale University campus and for some of the participants it has been the first time to get a look on a PET imaging center.

 


A street festival with lots of music and special food and last but not least the Volvo tennis tournament, where Mike was able to organize tickets for the participants of the symposium, were enjoyable social events. Plenty of sun and warm summer weather were accompanying the entire conference. For many of us it has been the first time to attend ATP-tennis at the center court, especially to see quarter- and semi-finals - with top-players as Boris Becker, Sergi Bruguera and Mats Wilander - of such an important tournament, which finally Andre Agassi won.
 
List of participants:
J. Arrighi, New Haven, USA; J. Banzo, Zaragoza, Spain; J. Barrett, N. Billerica, USA; M. Bernardo Filho, Rio de Janeiro, Brazil; T. Biscotti, Chatsworth, USA; J. Buscombe, London, UK; L. Coetzee, Bloemfontein, RSA; P.D. Crane, N. Billerica, USA; A. Crocker, N. Billerica, USA; E. Daher, New Haven, USA; D. Damphousse, N. Billerica, USA; P.A. de Lima, Rio de Janeiro, Brazil; M.K. Dewanjee, Miami, USA; H. Dey, New Haven, USA; K Eissler, Copiague, USA; M.R Fernandez Espina, Barcelona, Spain; M. D. Ezekowitz, New Haven, USA; A.M. Forster, Buckinghamshire, UK; R.S. Freitas, Rio de Janeiro, Brazil; A. Furno, Bologna, Italy; J. Glajeh, N. Billerica, USA; Susanne Granegger, Vienna, Austria; B. Gutfilen, Rio de Janeiro, Brazil; O. Hatano, Chiba, Japan; S. Hemingway, N. Billerica, USA; G. Karanikas, Vienna, Austria; J. Kuyama, Chiba, Japan; B.R. Line, Albany, USA; J. Lister-James, Londonderry, USA; J.T. Locher, Aarau, Switzerland; H. Louwes, Groningen, NL; J. Martin-Comin, Barcelona, Spain; J. McAfee, Rochester, USA; R.C. Mease, Washington, USA; A. Moisan, Rennes, France; G.J. Morrissey, London, Canada; B. Mosing, Vienna, Austria; B.R. Moyer, Londonderry, USA; K. Özker, Milwaukee, USA; H. Pieters, Bloemfontem, RSA; N. Prandini, Ferrara, Italy; T. Prangere, Lille, France; E. Prats, Zaragoza, Spain; T. Rees, Chatsworth, USA; M. Roca, Barcelona, Spain; E.K. Rocha, Rio de Janeiro, Brazil; Margarida Rodrigues, Vienna, Austria; C. Sampson, Cambridge, UK; A. Signore, Rome, Italy; H. Sinzinger, Vienna, Austria; Victoria E. Soroa, Buenos Aires, Argentina; S.C. Srivastava, Upton, USA; M.L. Thakur, Philadelphia, USA; K. Uno, Chiba, Japan; B.l. Zaret, New Haven, USA

 
8th Meeting Rome 1997:



The 8th ISORBE Congress, organised by Alberto Signore, was held from May 24th to 27th, 1997 in Castel Gandolfo, Rome. This international congress was devoted to the presentation and discussion of the latest advances in nuclear medicine in the study of infection, inflammation, atherosclerosis and thrombosis. The symposium was attended by 138 participants hailing from 27 countries. The scientific programme of the congress included a total of 117 presentations: 14 invited lectures, 42 oral papers and 61 poster presentations. All of these being presented during the course of an opening symposium, two basic inflammation and radiopharmacy sessions, four clinical inflammation/infection sessions, two atherosclerosis and thrombosis sessions and four poster sessions.
The organising committee wisely took the view that nuclear medicine should be inter-related with other medical specialities, so there were a number of clinical medical societies involved in the organisation, and the different working sessions benefited from the participation of clinical, physiological, pathological and immunological experts.
The Congress began with a symposium on the pathogenesis, diagnosis and treatment of atherosclerosis, given by Professors R. Ross, V. Fuster, H. Sinzinger and A. Corsini. During this symposium the most recent advances in the cellular and molecular bases of the condition, its pathogenesis and pharmacological control were discussed, as well as the role of nuclear medicine in this field. In the study of infection/inflammation special emphasis was given to research of new radiopharmaceuticals based on a better understanding of the pathophysiology of the inflammation, such as the studies carried out with cytokines and endothelial activation molecules.
In addition to the extensive scientific programme, those attending could also enjoy the wonderful countryside that surrounds the Villa Montecucco, especially Lake Albano, and make short visits to the Eternal City of Rome.
During the closing ceremony 4 prizes were awarded to the best presentations, with the winners being Doctors C. Van der Laken, E. Procaccini, S. Gratz and F. Jamar. In the choice of this pieces of research, devoted to cytokines labelling (interkeukin 1 and 2, endothelial activation molecules, anti-E selectin Fab) and new fragments of anti-granulocyte antibody, recognition was given to the search for future alternatives to conventional cell labeling techniques.
 
List of participants:
Alexander E., UK; Alonso-Farto J.C., Spain; Mrs. Alonso-Farto, Spain; Andreani D., Italy; Annovazzi A., Italy; Arca M., Italy; Archimandritis S.C., Greece; Arnold A., USA; Askienazy S., France; Askienazy M., France; Balink H., Holland; Barat J.L., France; Barone R., Rome; Barzin P.J., The Netherlands; Becker W., Germany; Behamdouni M., Canada; Bertrand-Barat J., France; Blower P.J., UK; Boccaletto F., Italy; Bowden A., UK; Buchmann M., Norway; Burroni L., Italy; Buscombe J.R., UK; Cangi, Italy; Castelli, Italy; Castorina L., Italy; Centi-Colella A., Italy; Cornaglia G., Italy; Chianelli M., Italy; Corsini A., Italy; Corstens F.H.M., The Netherlands; Crane P.D., USA; De Antoni M.G., Italy; D'Errico G., Italy; Ellis B., UK; Ezekowitz M., USA; Farrar G., UK; Fazio F., Italy; Fernandez Espina M.R., Spain; Forster A., UK; Furno A., Italy; Fuster V.; Galli G., Italy; Garganefe M.C.; Garron J.Y., France; Giacalone P.,Italy; Goldenberg D., USA; Granegger S., Austria; Grassi A.M., Italy; Gratz S., Germany; Gunasekera R., UK; GÜngor F., Turkey; Hauser W., Canada; Hoschl R., Australia; Hung J.C., USA; Iurilli A.P., Italy; Jamar F., Belgium; Jones J.M., UK; Kalauz M., Croatia; Karanikas G., Austria; Karonen S-L, Finland; Klem J.A., USA; Kotze H.F., South Africa; Lazzeri E., Italy; Leaver J.P., UK; Lee K.B., Korea; Leimer M., Austria; Liberatore M., Italy; Locher J., Switzerland; Maggi E., Italy, Martin-Comin J., Spain; Mather S.J., UK; Maurea S.,Italy; Maussier M.L., Italy; McAfee J., USA; Medina M., Italy; Mire-Sluis A., USA; Moisan A., France; Monton C., Spain; Moyer B.R., USA; Nardi G., Italy; Neumann I., Austria; Nielson J.T., Denmark; Ombresi D., Italy; Orlando P., Italy; Orlando V., Italy; Ormstead H.G., Norway; Overmyer T.A., UK; Oyen W.J.G, The Netherlands; Paganelli G., Italy; Pallone F., Italy; Parisella M.G., Italy; Pauwels E.K.J., The Netherlands; Pearce J.H., UK; Piffanelli A., Italy; Ponza F., Italy; Poropat M., Croatia; Poti C., Italy; Pozzilli P., Italy; Prandini N., Italy; Prangere T., France; Prats E., Spain; Procaccini E., Italy; Prosperi D., Italy; Rademacher T.W., UK; Roca M., Spain; Rodrigues M., Austria; Ronga G., Italy; Ross R.; Rouma G., Belgium; Sampson C., UK; Serra F., Italy; Squame F., Italy; Shapiro B., USA; Sharma H.L., UK; Sinzinger H., Austria; Sobal G., Austria; Soroa V.E., Argentina; Signore A., Italy; Spagnoli L., Italy; St Martin S., Canada; StrÖmberg S., Finland; Szasz, I., Canada; Thakur M.L., USA; Van Beers D., Belgium; Van der Laken C.J., The Netherlands; Van Haelst J.P., Belgium; van Wyk V., South Africa; Varraso Italy; Varoglu E., Turkey; Vaylet C., France; Ventroni G., Italy; Violi F., Italy; Wiseman G., USA; Zsinka L., Hungary.

 
9th ISORBE Congress Rio de Janeiro 1999




The 9th International Symposium on Radiolabeled Blood Elements has taken place from October 20th to 23rd, 1999 in the Campus of the Universidade do Estado do Rio de Janeiro, in Rio de Janeiro, Brazil. Rio de Janeiro is a beautiful city with famous beaches, hills, typical food, special music and pleasant people who live there. This was the first time that a scientific event of the International Society on Radiolabeled Blood Elements happened in Latin American. More than one hundred papers were presented as invited lectures or oral papers or posters of colleagues from several countries. There were 117 participants from Brazil and other far away countries, as Finland, Turkey and Australia. The 9th International Symposium on Radiolabeled Blood Elements has provided an excellent opportunity for the presentation and discussion of the latest achievements of nuclear medicine techniques and radiopharmaceuticals for the study of inflammation, infection, oncology and therapy using radiolabeled blood. The topics presented as invited lectures have permitted excellent discussions: (i) basic aspects of the inflammation process and the immunogenetics in the transplantation of organ, (ii) methods and the use of labeled antibodies, peptides and white blood cells in nuclear medicine, (iii) current US regulations and pharmacy practice standards applicable to blood element labeling in a commercial nuclear pharmacy, (iv) technetium-99m-labeled biotin and infecton, (v) nuclear medicine in the evaluation of ovarian and colon and rectal cancer and radiolabeled peptides for therapy, (vi) nuclear imaging in atherosclerosis, (vii) synthetic and bioengineered products in nuclear medicine and (viii) drug interaction in the labeling of red blood cells. There was a special lecture "Have faith in your radiopharmaceuticals - The Charles Sampson Memorial Lecture". The speaker was our colleague Malcolm Frier who emotionally presented his lecture to remember Charles Sampson. Dr. Mathew Thakur was responsible for the Scientific Committee to choose the best four papers, two oral and two posters, to be awarded. These were: 
  1. Synthesis, biodistribution and dosimetry studies of 123I-labelled annexin V in mice: a potential SPECT-ligand for visualisation of apoptotic cells. C. Lahorte, F. Dumont, G. Slegers, C. Van de Wiele, R.A. Dierckx from University of Gent, Belgium.
  2. Labelling of ceftizoxime with 99mTc. V. Gomes-Barreto, F. Iglesias, M. Roca, F. Tubau, J. Martin-Comin a collaboration between Spain and Brazil.
  3. Tc-99m HMPAO white blood cell scintigraphy in acute appendicitis patients with equivocal clinical presentation. F. Gungor, S. Ozugur, T. Colak, H. Bozan, A. Yildiz from Akdeniz University, Turkey.
  4. Labelling of the anti-elastin monoclonal antibody with technetium-99m using 2-iminothiolane. M.B.N. Oliveira, C.R. Silva, A.C. Braga, A. Caldeira-de-Araujo, M. Bernardo-Filho from University of Rio de Janeiro, Brazil.

Symposium Participants:
Prangere Thierry, Sirkka-Liisa Karonen, Kairemo Kalevi, Veiga Jorge, Lasa Perez Dionisio, Granegger Susanne, Tomas Maria, Cavalcante Carlos, Locher Johannes, Palestro Christopher, Sobal Grazyna, Ramos Farias Moreno Silvana, Linkowski Faintuch Bluma, Dantas Flavio, Zabala Prisila, Capriles V.S., Prandini Napoleone, Moisan Annick, Ozker Kutlan, Firat Gungor Ahmet, Baptista Santos Marco Aurelio, de Oliveira Chavez Erika Cristina, Hiller Bondarczuck Marli, Lahorte Christophe, Sciavom Duarte Paulo, Moraes Rogerio, Barat Bertrand, Frier Malcolm, Ertay Turkan, Diniz Simone, Leite Bruno, Franca de Mendonca Elitom, de Oliveira Aguiar Ronaldo, Dere Feliciano Glaucio, Burroni Luca, Gunasekera R., de Labriolle-Vaylet Claire, Ripoll Hamer Erica, Alonso-Farto Juan Carlos, Carneiro Michel, Nigri Flavio, Ferreira da Costa Rosario, Souza O. Jose Eduardo, de Souza Maciel Oduwaldo, Forstrom Lee, Serafim R. Bernardo, Camargo Bernardo Luciana, Varraso Antonio, Prats Enrique, Cardoso de Souza Conceicao Rejane, Braga A.C.S., Avila A.S., Caldeira de Araujo Adriano, Signore Alberto, Buchpiguel Carlos Alberto, Ribeiro da Silva Claudia, Pagano G. da Silva Constancia, Pearson Daniel, Tabak Daniel, Machado do Mattos Deise Mara, Regio Moraes Edison, Boasquevisque Edson, Kotlyarov Eduard, Garcia Eloy J., Verdera Presto Emilia Silvia, Braga Francisco, Sinzinger Helmut, Oliveira Joelma F., Buscombe John R., Martin-Comin Jose, Oliva Gonzales Juan P., Britton Keith E., Seifert Katherine L., Oliveira Marcia B.N., Younes Ibrahim M., Roca Engronat Manuel, Rodrigues Margarida, Exposito Penas Maria, Gomes Maria Luiza, Bernardo Filho Mario, Thakur Mathew L., Stabin Michael, Boerman Otto C., Gonzales Espinoza Patricio Orlando Jose, Baum Richard, Levy Cavalcanti Jales Roberto, de Souza Freitas Rosemeire, Das Satya S., Cardoso Albert N., Soroa Victoria Ester, Oyen Wim J.G., Rodrigues Motta Anna Paula, Aleixo Luis Claudio, Bastos Miguel Angelo, Braghiroli Ana Maria, Laufer Gustavo, Pecanha Muzy Dias Aline, Moreira Monamaldo Costa Thadeu Estevam, Figueiredo Soares Scheila, Figueiredo de Melo Suzana, Masioli Marco Antonio, dos Santos Lins Gean Bernardo Xavier, Salehi Nouria, Theodoro Boullosa Lidia, Roberto Avila C. Bezerra Jose, Ribeiro Madke Rafael, Almeida Maria Janilde, Ferreira da Costa Rogerio, Shaskolsky I., Lazzeri Elena, Nilson Elisa, Vivante Hugo A., Fonseca Souza Joseane, Paiva Proenca Martins Flavia, Nicolini Jorge Oswaldo, Manhaes de Souza Ricardo A., Miranda Jose R. A..
 

 TIME-TABLE OF CONFERENCES

1st International Symposium on Radiolabeled Blood Cells.
September 1979, Yale

University School of Medicine, New York, USA.
Organization: M.L. Thakur, A. Gottschalk
Proceedings: In-111 labeled neutrophils, platelets and lymphocytes. Eds.: M.L. Thakur, A. Gottschalk, Trivirum Pub. Co., New York, 1980.
 

2nd Radiolabeled Cellular Blood Elements.
August 29 - September 9, 1982, Maratea, Italy, NATO ASI

Organization: M.L. Thakur, M.D. Ezekowitz, M.R. Hardeman
Proceedings: Radiolabeled cellular blood elements. Eds.: M.L. Thakur, M.R Hardeman, M.D. Ezekowitz. Plenum Pub. Co., New York, 1985
 

3rd Conference on Radionuclide Labeled Cellular Blood Elements: Application in Atherosclerosis and Thrombosis.
February 3 - 6, 1986, University of the Orange Free State, Bloemfontein, South Africa

 Organization: A. du P. Heyns, P.N. Badenhorst, M.G. Lotter
Proceedings: Conference on radionuclide labeled cellular blood elements: Applications m Atherosclerosis and Thrombosis. Ed.: A. du P. Heyns. Publ.
South African Medical Research Council, Parow, 1986.
 

4th International Symposium on Radiolabeled Platelets.
May 28 - 29, 1987, Hotel Mondial, Cologne, Germany

Organization: J.N. Petrovici, Ch. Kessler, G. Modder
Proceedings: Clinical Applications of Radiolabeled Platelets. Eds.: Ch. Kessler, M.R
Hardeman, K Hennmgsen, J.N. Petrovici. Kluwer Academic Publ., Dordrecht, NL, 1990.
 

5th International Symposium on Radiolabeling of Cellular Blood Elements.
September 10 - 14, 1989, Vienna, Austria
Foundation of the INTERNATIONAL SOCIETY OF RADIOLABELED BLOOD ELEMENTS (ISORBE)

 First President: Mathew L. Thakur
Organizing Chairmen: H. Sinzinger and M.L. Thakur
Local Organization: P. Fitscha, Ch. Miiller, Eva Strobl-Jager, Irene Virgolini, V. Weiler 
Abstracts: Nuclear Medicine Research Vol 3. RadiolabeRed Cellular Blood Elements. Eds.: KF. Sinzinger, M.L. Thakur.
Proceedings: Progress in Clinical and Biological Research. Vol. 355. Radiolabeled Cellular Blood Elements. Eds.: H. Sinzinger, M.L. Thakur.
Publ Wiley-Liss Inc. New York, 1990.
 

6th International Symposium on Radiolabeled Blood Elements.
NATO Advanced Research Workshop. November 23 - 27, 1992, Barcelona, Spain

Second President: Helmut Sinzinger
Advisory Council: M.L. Thakur, J.G. McAfee, H. Sinzinger, J. Martin-Comin
Local Organization: J. Martin-Comin, M. Roca, C. Piera, F. Lomena
Proceedings: Radiolabeled Blood Elements. Recent advances in techniques and applications.
Eds.: J. Martin-Comin, M.L. Thakur, C. Piera, M. Roca, F. Lomena. NATO ASI series vol. 262, Plenum Press, New York, 1994.
 

Pre-congress Meeting during the European Association of Nuclear Medicine Congress
August 20, 1994, Düsseldorf; Germany

 Organization: H. Sinzinger
 

7th International Symposium on Radiolabeled Blood Elements.
August 16 - 19, 1995, Yale University, New Haven, USA

Third President: Jose Martin-Comin
Honorary President: John G. McAfee
Course Director: M.D. Ezekowitz
Local Organization: M.D. Ezekowitz, J. Arrighi, Holley Dey, R Soufer, B.L. Zaret
Proceedings: Have not been published
 

Pre-congress Meeting during the European Association of Nuclear Medicine Congress
September 14, 1996, Copenhagen, Denmark

Organization: A. Signore, M. Chianelli
 

8th International Symposium on Radiolabeled Blood Elements.
May 24 - 27, 1997, Rome, Italy

 Organizing President: A. Signore
Local Organization: M. Arca (Secretary), M. Chianelli, M. Liberatore, Maria L. Maussier, G. Paganelli, A. Piffanelli, P. Pozzilli, G. Ronga
Honorary Committee: D. Andreani, P. Biglioli, P. Bianchi, G. Camuzzini, A. Centi Colella, G. Faglia, F. Fazio, G. Galli, M. Gandolfi, G. Ricci
Scientific Committee: S. Askienazy, W. Becker, F. Corstens, M. Ezekowitz, J. Martin-Comin, S.J. Mather, A. Piffanelli, H. Sinzinger, S. Srivastava, M.L. Thakur, F. Violi
Abstracts: Nuclear Medicine Communications
Proceedings: Not decided at time of printing

 
9th International Symposium on Radiolabeled Blood Elements.
October 20-23, 1999 Universidade do Estado do Rio de Janeiro, Campus Rua São Francisco Xavier, 524 Rio de Janeiro, RJ, Brazil

 Organizing President: M. Bernardo-Filho
Coordinator: E. Mendes Boasquevisque
Organizing Committee: M. Chianelli, P. Gonzales, M. Frier, Margarida Rodrigues, Victoria E. Soroa, S. Verdera, S. Srivastava
Local Committee: A.M. Braghirolli, A.C. de Araújo, C. Buchpiguel, C.R. Silva, C. Pagano, J.E. Pereira, J.F. Oliveira, M.B. Oliveira, M. Exposito Penas, M. Albernaz,
M. Rebelo, R.J. Bezerra
Scientific Committee (International): W. Becker, J. Buscombe, J. Martin-Comin, A. Signore, H. Sinzinger, M. Thakur
Scientific Committee (Local): V.C. Nascimento, F. Braga, R.L. Jales, E.A. Araújo, M. Bernardo-Filho, E.M. Boasquevisque, M.A. Martins, C.A. Lacerda
Abstracts: Published in Nuclear Medicine Communication
 

 BOARD OF ISORBE

1989 - 1992
President:
Mathew L. Thakur (Philadelphia, USA)

Secretary:
John G. McAfee(Washington, USA)

Treasurer:
Helmut Sinzinger (Vienna, Austria)

 Executive Committee:
W. Becker (Erlangen, Germany), M.K Dewanjee (Miami, USA), M.E. Ezekowitz (New Haven, USA), D.A. Goodwin (Palo Alto, USA), M. Hardeman ( Amsterdam,
The Netherlands), A. du P. Heyns (Bloemfontein, South Africa), C. Kessler (Koln, Germany), P. Lavender (London, U.K.), J. Martin-Comin (Barcelona, Spain),
A.M. Peters (London, U.K.), K. Uno (Chiba, Japan)
 

 1992 -1995
President:
Helmut Sinzinger (Vienna, Austria)

Immediate Past President:
Mathew L. Thakur (Philadelphia, USA)

Secretary:
Michael D. Ezekowitz (New Haven, USA)

Treasurer:
Jose Martin-Comin (Barcelona, Spain)

Board of Directors:
P.N. Badenhorst (Bloemfontein, South Africa), R. Baum (Frankfurt, Germany),W. Becker (Göttingen, Germany), F. Corstens (Nijmegen, The Netherlands), M. K. Dewanjee (Miami, USA), A. Driedger (London, Canada), M.C. Gil (Santiago, Chile), D.A. Goodwin (Palo Alto, USA), M. Hardeman (Amsterdam, The Netherlands), Daya K. Hazra (Agra, India), A. du P. Heyns (Bloemfontein, South Africa), R.M. Lambrecht (Sidney, Australia), J.P. Lavender (London, U.K), J.T. Locher (Aarau, Switzerland), F. Lomena (Barcelona, Spain), J.G. McAfee (Bethesda, USA), A. Moisan (Rennes, France), A.M. Peters (London, U.K.), A. Signore (Rome, Italy), K. Uno (Chiba, Japan)


1995-1997
President:
Jose Martin-Comin (Barcelona, Spain)

Honorary President:
John McAfee (Bethesda, USA)

Immediate Past President:
Helmut Sinzinger (Vienna, Austria)

Secretary:
Alberto Signore (Rome, Italy)

Treasurer:
Wolfgang Becker (Göttingen, Germany)

Board of Directors:
P.N. Badenhorst (Bloemfontem, South Africa), M. Bernardo-Filho (Rio de Janeiro, Brazil), F. Corstens (Nijmegen, The Netherlands), M. K. Dewanjee (Miami, USA), M.D. Ezekowitz (New Haven, USA), Maria Cecilia Gil (Santiago, Chile), D.A. Goodwin Palo Alto, USA), Daya K. Hazra (Agra, India), R.M. Lambrecht (Sidney, Australia), J.T. Locher (Aarau, Switzerland), Annick Moisan (Rennes, France), A.M. Peters (London, U.K), E. Prats Rivera (Zaragoza, Spain), Margarida Rodrigues (Vienna, Austria), C.B. Sampson (Cambridge, U.K.), Victoria E. Soroa (Buenos Aires, Argentina), S.C. Srivastava (Upton, USA), K. Uno (Chiba, Japan)

 

1997-1999
President:
Wolfgang Becker (Göttingen, Germany)

Honorary President:
John McAfee (Bethesda, USA)

Immediate Past President:
Jose Martin-Comin (Barcelona, Spain)

Secretary:
John Buscombe (London, UK)

Treasurer:
Margarida Rodrigues (Vienna,Austria)

Board of Directors:
P.N. Badenhorst (Bloemfontein, South Africa), M.D. Ezekowitz (New Haven, USA), M.C. Gil (Santiago, Chile), C.B. Sampson (Cambridge, UK), K. Uno (Chiba, Japan), S.C. Srivastava (Upton, USA), Daya K. Hazra (Agra, India), M. Chianelli (Rome, Italy), F. Corstens (Nijmegen, NL), R.M. Lambrecht (Sidney, Australia), Victoria E. Soroa (Buenos Aires, Argentina), M.K. Dewanjee (Miami, USA), A. Moisan (Rennes, France), D.A. Goodwin (Palo Alto, USA), M.A. Peters (London, UK), M. Bernardo-Filho (Rio de Janeiro, Brazil), J.T. Locher (Aarau, Switzerland), E. Prats Rivera (Zaragoza, Spain)

 

1999-2001
President:
Alberto Signore (Rome, Italy)

Honorary President:
John McAfee (Bethesda, USA)

Immediate Past President:
Wolfgang Becker (Göttingen, Germany)

Secretary:
Enrique Prats Rivera (Zaragoza, Spain)

Treasurer:
Margarida Rodrigues (Vienna, Austria)

Board of Directors:
P.N. Badenhorst (Bloemfontein, South Africa), M. Bernardo-Filho (Rio de Janeiro, Brazil), J. Buscombe (London, UK), F. Corstens (Nijmegen, NL), M.K. Dewanjee (Miami, USA), M.D. Ezekowitz (New Haven, USA), M.C. Gil (Santiago, Chile), D.A. Goodwin (Palo Alto, USA), K. Azra (Agra, India), R.M. Lambrecht (Sidney, Australia), J.T. Locher (Aarau, Switzerland), A. Moisan (Rennes, France), W. Oyen (Nijmegen, The Netherlands), M.A. Peters (London, UK), V.E. Soroa (Buenos Aires, Argentina), S.C. Srivastava (Upton, USA), K. Uno (Chiba, Japan)
 

 PAST PRESIDENTS

1989 - 1992: Mathew L. Thakur




1992 - 1995: Helmut F. Sinzinger




1995 - 1997: José Martin-Comin




1997 - 1999: Wolfang Becker (♦ 2002)




1999 - 2001: Alberto Signore




2001 - 2003: Margarida Rodrigues




2003 - 2007: Christopher Palestro




2007 - 2011: Victoria Soroa








 

Obituaries

 Wolfgang BECKER (1952 – 2002)


 

Wolfgang BECKER was born on September 7th, 1952 in Uffenheim, Bavaria, Germany. In 1971 he passed the “Abitur” (school-leaving examination) at Bad Windsheim and got the MD at the University of Würzburg in 1979. He worked shortly at the Department of Pathology and specialized in Nuclear Medicine from 1981 to 1985 at the Department of the University of Würzburg under Prof. W. Börner. The topic of his “Habilitation” (augural thesis) in 1987 was one of his key scientific interests (“111Indium-oxine labelling of white blood cells, potential of scintigraphic diagnosis in inflammatory diseases”).
In 1988 he became C3 Professor for Nuclear Medicine at the University of Erlangen, Nürnberg and in 1995 C4 Professor for Nuclear Medicine at the Georg August University of Göttingen, where he stayed until his death.
He became member of the Task Group on Continuous Education of the European Association of Nuclear Medicine (EANM) in 1991, another key interest in his life. This involvement finally led to the position of the Dean of the European School of Nuclear Medicine in 1995 and the Vice-presidency of the Union of the European Medical Specialists.
In 1997 he was elected president of ISORBE, the International Society on Radiolabeled Blood Elements. In ISORBE he had a lot of very close fiends sharing his interest on radiolabeling blood cells from the early beginning in the early 80ies.
In 1998 he was elected as president of the Union of the European Medical Specialists and in 1999 of EANM.
On May 18th, 2002 Wolfgang Becker died after a long and courageous battle against cancer.
He is survived by his wife Hedwig, they married 1978, and his two children Sabine (born 1980) and Sebastian (born 1982).
Wolfgang Becker was an excellent scientist, a great supporter of young researchers, a pioneer in education and above all an outstanding personal character, colleague and friend.
 
 

Johannes Theophil LOCHER (1938 - 2007)

Johannes T. LOCHER was born on the 5th of March, 1938 in Schaffhausen, Switzerland. After finishing school with "Abitur" in Basle in 1958 he studied medicine at the Universities of Geneva, Basle and Bern where he obtained his degree. Starting in internal medicine he discovered his interest for the young discipline of nuclear medicine by chance and obtained a position at the Department of Nuclear Medicine in Basle.
In 1974 he was the first in Switzerland to become Associate Professor (habilitation) for nuclear medicine. In the same year he was appointed Director of the Nuclear Medicine Department in Aarau giving him the opportunity to establish and form the institution from the early beginning. His very kind and friendly personality allowed among others a cooperation integration of nuclear medicine into the local medical structure. His long efforts to establish PET at this unit was achieved only shortly after his retirement (March 30th, 2003) which was celebrated on January 17th, 2003 at a national symposium. 
Johannes Locher was the first president of the section of Nuclear Medicine of the Swiss Society for Radiology from 1979 to 1983. From 1998 to 1999 he was secretary and thereafter until 2003 the president of the Swiss Society for Nuclear Medicine.
Johannes Locher became closely related to the ISORBE family with his pioneer work being the first to use white blood cell antibody for diagnosis of infection. At the 5th ISORBE Meeting in Vienna 1989 he was already presenting his plentyful experience and from then on he was attending all the ISORBE Conferences including the last one in September 2005 in Villigen, Siwtzerland, which he organized and hosted (together with P. August Schubiger). From 1992 to 1997 Johannes Locher was a member of the Board of Directors of ISORBE.
One of his particular hobbies was to help to establish nuclear medicine in the formerly communistic countries mainly in Bulgaria. In particular he was proud when he succeeded in establishing an academy for radiological technicians in Varna, Bulgaria. These activities have been recognized by a honorary doctor degree at the University of Varna in 1999.
In 2001 he received the "Von Hevesy-medal" from the Hungarian Society of Nuclear Medicine.
Johannes Locher was a kind, polite, benevolent person, intelligent and educated with wide interests. His knowledge and cultural education were enormous. It was a too rare pleasure to have dinner with him and touch a wide spectrum of ideas, interests and plans. He was well respected and he was always ready to listen to the people's opinion. He was a critical scientist, a good listener, calm and helpful colleague and supportive friend. His enegery, ideas and plans for the time after retirement due to his multiple interests were large. It was a privilege to share science, projects and time with him.
ISORBE lost one of its closest family members, a long-lasting supporter and a good friend.

Helmut Sinzinger, Vienna in May 2007
in: ISORBE Newsletter. Radiolabelled Blood Elements 2007; Vol 13(No 1): 10-11

 

John Mc AFEE (1926 - 2008)

 

      

                                                                   in: ISORBE Newsletter. Radiolabelled Blood Elements 2008; Vol 15(No 1): 5-6




 

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